| Spirit of MK | 33.5 | 1980 | CRN |
| Spirit of Fortitude | 34.14 | 1997 | Karadeniz |
| Spirit du Brazil VIII | 35.37 | 2009 | Pershing S.p.a. |
| Spirit | 54.35 | 2011 | Amels |
| Spirit | 34 | 2010 | Westport Yachts |
| Spiip | 28.27 | 2024 | Nautor Swan |
| Spice Of Life | 31 | 1994 | Aegean Builders |
| Spica | 30.13 | 2023 | Ferretti Yachts |
| Spes Nostra | 27.8 | 1988 | Jongert Yachts |
| Speranza II | 28.93 | 2021 | Sanlorenzo |
| Spellbound | 34.98 | 2009 | Admiral |
| Speculator | 28.42 | 2016 | Viking Yachts |
| Spectre | 28.15 | 2015 | Sunseeker |
| Spectre | 69.2 | 2018 | Benetti SpA |
| Spectre | 33 | 2009 | Sanlorenzo |
| Spectre | 30.5 | 2016 | AB Yachts |
| Special One | 52 | 2024 | Royal Huisman |
| Special K | 31 | 2013 | Italyachts |
| Spear Sea II | 30.54 | 1992 | Jones-Goodell Corporation |
| Sparta | 67 | 2023 | Heesen Yachts |
| Sparkling | 33 | 2009 | Sanlorenzo |
| Space Y | 47 | 2006 | Heesen Yachts |
| Space Oddity | 28.14 | 2003 | Sunseeker |
| Space Cat | 35.9 | 2022 | Silver Yachts |
| Sovereign Lady II | 29.87 | 2008 | Horizon Yachts |
| Sovereign Lady | 36.57 | 1991 | Broward Marine |
| Sovereign | 29.57 | 1966 | Burger Boat Company |
| Southwind Of | 41.55 | 1999 | Jongert Yachts |
| Southern Way | 34.74 | 2005 | Nordlund Boat Company. Inc. |
| Southern Star | 28.04 | 1974 | Burger Boat Company |
| Southern Star | 31.09 | 2013 | Hatteras Yachts |
| Southern Cross II | 34 | 1983 | Lloyds Ships |
| Southern Cross | 33.4 | 1962 | Yarrow & Co |
| Southern Cross | 29.7 | 1991 | CIM - Constructions Industrielles et Maritimes |
| Southern Cross | 45 | 1996 | Niigata Shipyard |
| Southern Cloud | 39.72 | 1990 | Faenoe |
| Southern Brew | 29.44 | 2006 | Cheoy Lee |
| South Paw C | 34.65 | 1977 | Codecasa S.p.A. |
| South China Sea Welkin | 34 | 2012 | Custom Line |
| South | 33 | 2020 | Custom Line |
| South | 55 | 2012 | Heesen Yachts |
| Souraya | 37.2 | 2012 | Sanlorenzo |
| Sounion II | 31.62 | 1969 | Benetti SpA |
| Soundwave | 63 | 2015 | Benetti SpA |
| Soulmate | 34.3 | 2015 | DL Yachts |
| Souldmate | 30.75 | 2000 | Azimut Yachts |
| Soul | 28.29 | 2001 | Hatteras Yachts |
| Sorridente | 28.96 | 2010 | Azimut Yachts |
| Sorrento | 62 | 2010 | Benetti SpA |
| Sorcha | 46.3 | 2005 | Northern Marine Co. LLC |
